Title: Research Technician II-Molecular Biology
Location: Upper East Side
Org Unit: Tri-Institute-TDI
Work Days: Monday-Friday
Exemption Status: Non-exempt
The Tri-Institutional Therapeutics Discovery Institute (Tri-I TDI) seeks a highly motivated and enthusiastic individual to be a member of the Antibody Engineering Team. The Tri-I TDI, a partnership of Memorial Sloan Kettering Cancer Center, The Rockefeller University, and Weill Cornell Medicine, links researchers in basic and clinical science with experts in drug discovery from the biotech and pharmaceutical industries, with the goal of more efficiently translating discoveries into therapies for disease. The molecular biology position will support antibody discovery and lead optimization efforts across the biologics portfolio through cloning, expression vector and protein design, sequencing, and optimization of biologic drug properties. The Research Associate will work closely with teams across the biologics division and academic collaborators and present data to the project teams.
- Performs plasmid purifications, polymerase chain reactions and molecular cloning.
- Designs primers for PCR, sequencing and mutagenesis.
- Generates plasmids for recombinant antibody and antigen production in bacterial and mammalian cell culture systems.
- Maintains an inventory of bacterial cultures, plasmids, primers and other reagents.
- Records experimental methods, results and conclusions.
- Is active in managing day-to-day laboratory needs and maintaining SOPs.
- Stays current with literature and emerging trends in the discipline.
- Performs other related duties as assigned.
- Bachelor’s Degree in related field
BS/MS in molecular biology, biochemistry, chemical engineering or related field.
A minimum of 2 years laboratory experience in molecular biology in an academic
laboratory, or in the pharmaceutical or biotechnology industry.
Experience in molecular cloning techniques (PCR, plasmid preparation, DNA
sequence analysis), and with handling and manipulating microbial cultures.
Knowledge of molecular construct design using nucleic acid and protein analysis
Previous experience with bacterial and mammalian cell culture handling.
Proficiency with enzyme-linked immunosorbent assay (ELISA) and Western Blot.
Understanding of antibody structure and function.
Knowledge, Skills and Abilities
- Motivation to learn and grow in scientific expertise.
- Ability to manage work with minimal supervision.
- Ability to trouble-shoot technical issues.
- Strong communication and presentation skills.
- Ability to work on multiple projects simultaneously.
Weill Cornell Medicine is a comprehensive academic medical center that’s committed to excellence in patient care, scientific discovery, and the education of future physicians in New York City and around the world. Our doctors and scientists-faculty from Weill Cornell Medical College, Weill Cornell Graduate School of Medical Sciences, and the Weill Cornell Physician Organization-are engaged in world-class clinical care and cutting-edge research that connect patients to the latest treatment innovations and prevention strategies. Located in the heart of the Upper East Side’s scientific corridor, Weill Cornell Medicine’s powerful network of collaborators extends to its parent university Cornell University; to Qatar, where an international campus offers a U.S. medical degree; and to programs in Tanzania, Haiti, Brazil, Austria and Turkey. Our medical practices serve communities throughout New York City, and our faculty provide comprehensive care at NewYork-Presbyterian Hospital/Weill Cornell Medical Center, NewYork-Presbyterian/Lower Manhattan Hospital, and NewYork-Presbyterian/Queens. At Weill Cornell Medicine, we work together to treat each individual, not just their conditions or illnesses, as we strive to deliver the finest possible care for our patients – the center of everything we do. Weill Cornell Medicine is an Equal Employment Opportunity Employer. Weill Cornell Medicine provides equal employment opportunities to all qualified applicants without regard to race, sex, sexual orientation, gender identity, national origin, color, age, religion, protected veteran or disability status, or genetic information.